tert-butyl trans-(2-(4-bromophenyl)cyclopropyl)carbamate - Names and Identifiers
tert-butyl trans-(2-(4-bromophenyl)cyclopropyl)carbamate - Physico-chemical Properties
tert-butyl trans-(2-(4-bromophenyl)cyclopropyl)carbamate - Introduction
(±)-trans-O-tert-butyl-N-(2-(4-bromophenyl) cyclopyl) carbamate is an organic compound commonly abbreviated as BTCA. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-molecular formula: C15H19BrNO2
-Molecular weight: 333.22g/mol
-Melting point: 90-92 ° C
-Boiling point: 322-323 ° C
-Solubility: Slightly soluble in water, soluble in many organic solvents
Use:
- BTCA is commonly used as a reagent in organic synthesis to synthesize and modify compounds such as drugs, pesticides and biologically active molecules.
-Because BTCA has good trans stereoselectivity, it plays an important role in the organic synthesis of enantiomers.
Method:
BTCA can be prepared by the following steps:
1. 4-Bromobenzoic acid is reacted with cycloacetone to obtain cyclopropyl benzoic acid.
2. In the presence of a base, cyclopropylbenzoic acid reacts with tert-butyl alcohol to generate O-tert-butyl-N-(2-(4-bromophenyl) cyclopyl) carbamate.
Safety Information:
- BTCA is an organic compound and has a certain degree of danger.
-Appropriate protective measures should be taken during operation, such as wearing chemical protective gloves and goggles.
-Avoid contact with skin and inhalation of gases, fumes or dust containing the compound.
-Pay attention to avoid fire and high temperature during use and storage.
-If taken by mistake or discomfort occurs, seek medical attention immediately.
Last Update：2024-04-09 21:04:16